Dr. Louis M. Weiner, MD

Dr. Louis M. Weiner, MD

Dr. Louis M. Weiner, MD

Languages: English
Phone: 202-444-2223
Fax: 202-444-1229

Contact this Provider:

  • Gastrointestinal Medical Oncology
  • Medical Oncology
Conditions I Treat
  • abdominal cancer
  • anal cancer
  • anorectal cancer
  • appendiceal cancer
  • bile duct mass
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Procedures I Perform
  • adjuvant chemotherapy
  • biologic therapy for gastrointestinal diseases
  • biological targeted therapy
  • cancer chemotherapy
  • cancer genomics
  • Show All
About the Provider

Dr. Weiner is an internationally-recognized medical oncologist specializing in gastrointestinal cancers. He is also an accomplished researcher developing novel immunotherapy treatments – essentially triggering the body’s own immune system to identify and destroy cancer. He is recognized for his laboratory and clinical research focusing on these new therapeutic approaches. Dr. Weiner wants to understand why some tumors become resistant to therapy and other forms of cancer immunotherapy, with the goal of developing new treatments to overcome that resistance. He lectures extensively on these forms of targeted therapies, which block the growth and spread of cancer.

He serves as director of the Georgetown Lombardi Comprehensive Cancer Center – Washington, D.C.’s only National Cancer Institute-designated comprehensive cancer center – and the MedStar Georgetown Cancer Institute, which combines medical expertise, the latest therapies, and research across MedStar Health throughout the region. Dr. Weiner is also associate vice president at Georgetown University Medical Center, chair of the oncology department at Georgetown University School of Medicine, and clinical director of cancer services at MedStar Georgetown University Hospital.

In these roles, Dr. Weiner is responsible for operations, development, research, clinical and educational missions. As the Institute’s director, he oversees the clinical operations of the MedStar Health cancer service line, and leads the advancement of clinical care and research programs spanning prevention, treatment, rehabilitation, survivorship and end-of-life care across the region. With Georgetown Lombardi serving as the Institute’s “research engine,” patients throughout the region have access to unmatched expertise and clinical trials closer to where they live and work.

Dr. Weiner previously served as chairman of the Medical Oncology Department and vice president for Translational Research at Fox Chase Cancer Center in Philadelphia, PA. He held an endowed chair in medical science and was the driving force behind developing an immunotherapy laboratory and clinical programs, as well as establishing the Center's medical oncology fellowship program. Dr. Weiner also served as professor in the Department of Medicine at Temple University School of Medicine.

Dr. Weiner's Philosophy of Care
We live in a time of great hope in the area of cancer therapy. Many new, important and life-changing treatments are now being developed. We are privileged to offer patients tomorrow's treatments today. And now, through the MedStar Georgetown Cancer Institute, we can extend that mission across the region. With this progress in mind, I strive to offer all my patients the best possible therapies for their diseases, always mindful that I am neither treating a disease nor a patient, but a person with a life, a family and a combination of hopes and fears.

Working at a great cancer program like this gives me the opportunity to collaborate with leading international experts to assure that my patients can benefit from the best possible care during the course of their journeys.

  • Fellowship Program: New England Medical Center Hospitals (1982)
  • Residency Program: Fletcher Allen Health Care (1981)
  • Internship Program: Fletcher Allen Health Care (1978)
  • Medical School: Mount Sinai School of Medicine (1977)
  • Board Certification: American Board of Internal Medicine, Medical Oncology
  • Board Certification: American Board of Internal Medicine, Internal Medicine

Dr. Weiner has authored more than 200 publications throughout his career centering on the following core topics:

Enhancing Antibody Dependent Cellular Cytotoxicity (ADCC) as an Anti-Tumor Mechanism

Manipulating Antibody Structure to Improve Selective Tumor Targeting

Identifying Tumor Cell-Based Determinants of Antibody-Mediated Cell Killing

Immunoconjugates for Cancer Therapy

Antibody-initiated Cancer Immunotherapy

Click here for a complete list of his research papers and scientific contributions. 

    MedStar Health Providers participate with a wide range of health insurance products. We accept self-pay patients and the insurances plans listed below. This list is not comprehensive, it is updated periodically and is subject to change. If you do not see your health insurance plan or product listed, or if you have any questions regarding MedStar Health’s participation with your health plan, please contact your health plan to verify participation with our providers.

    Since the MedStar Health providers span the District of Columbia, Maryland and Virginia regions, our participation with DC, Maryland and Virginia Medical Assistance programs varies by provider group. Please contact your MedStar Physician’s Office to assist with verifying Medical Assistance participation. If you are enrolled in a Medicaid Managed Care Organization, please contact your Medicaid health plan to verify participation.

Practice Locations
  • 3800 Reservoir Road Northwest
    Lombardi Cancer Center
    Washington, DC 20007
    View Map

    Phone: 202-444-2223
    Fax: 866-495-1112

Member of Medical Staff
  • MedStar Georgetown University Hospital
  • Castle Connolly Top Doctors, 2021
  • National Academy of Inventors Fellow, 2017-2018
  • Recognition for Outstanding Contribution to Innovation and Commercialization, Georgetown University, Office of Technology, 2016
  • Fellow, American College of Physicians, 2010
  • America’s Top Oncologists, 2009               
  • America’s Top Doctors for Cancer, 2007 – Present
  • Philadelphia Magazine's Top Docs, 2002; 2004 – 2007
  • Who's Who in Medicine and Healthcare, 2002 - 2005
  • G. Morris Dorrance, Jr. Endowed Chair in Medical Science, 2002
  • American Association for Cancer Research Scientist-Survivor Program Award, 2002
  • American Cancer Society - Southeast Region Scientific Research Award, 2002
  • Janssen Pharmaceutical Research Foundation: Research Award for Outstanding Contributions to the Field of Receptor Targeted Therapy, 2001
  • Best Doctors in America, 2000-2011
  • National Cancer Institute Clinical Investigator Award, 1986
  • American Cancer Society Career Development Award, 1985